Beilstein J. Org. Chem.2013,9, 1127–1134, doi:10.3762/bjoc.9.125
; monosubstitutedphenylboranes; phenylboronic acids; Introduction
Boronic acid derivatives have been widely studied because of their good performance as pharmaceutical agents, serving in the development of enzyme inhibitors of peptidases/proteases, proteasomes, arginase, nitric oxide synthase (NOS), and
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Graphical Abstract
Figure 1:
2- and 4-fluorophenylboronic acids (1 and 2) and 2-substituted phenylboranes [X = F (3), Cl (4), Br...